MethylPro®’s Magnesium Glycinate is a bioavailable form of magnesium that supports restful sleep and a relaxed mood. This essential mineral has a wide range of biological functions including a role as cofactor for several enzymes in healthy methylation reactions, including as a cofactor for the COMT enzyme, involved in normal neurotransmitter breakdown. People with sensitivity to magnesium citrate may tolerate magnesium glycinate. A significant percentage of the population struggles to get enough magnesium in their diet. Sleep Well: Magnesium supports normal levels of calming GABA and normal muscle contraction leading to a restful night.*. Healthy Stress Response: Magnesium supports calm via its action on several key mediators of the physiological stress response and is involved as a cofactor in the breakdown of stress responsive catecholamine neurotransmitters.*. Calm Cortisol: Magnesium affects neurotransmission in a way that calms the cortisol response.