Female infertility is a contributing factor for about one third of infertility cases. The cause of female infertility is linked to ovulation problems and damage to fallopian tubes, which indicates lack of health of the reproductive system in general. These symptoms are mainly reflected in the quality and number of oocytes, which are diminished in an impaired reproductive system. The oocyte has the highest number of mitochondria and mitochondrial DNA copies of any cell. The status and function of mitochondria is crucial to oocyte quality, fertilization of oocyte, and embryo development. Poor oocyte quality is one of the leading causes of failed in vitro fertilization (IVF). Other fertilization techniques such as intrauterine insemination (IUI) are also heavily dependent on ovulation cycles and oocyte quality. Disorders in reproductive system are also characterized by further complications such as polycystic ovary disease (PCOS), accompanied by hyperandrogenism, insulin resistance, abnormal lipid profile and oxidative stress. Oocyte health impacts reproductive and overall health beyond fertility. Previous treatments for infertility and PCOS with clomiphene citrate and gonadotropins are not without their own complications, and a natural and safe alternative is required to improve oocyte quality and reproductive health.