5-MTHF, provided as Quatrefolic, is the most biologically active form of the water-soluble B vitamin, folic acid. It is the preferred form of folate supplementation due to an array of conditions that can limit conversion or absorption of folic acid. Data indicate that supplementing with 5-MTHF increases plasma folate more effectively than folic acid.*

Consult your healthcare professional prior to use if you have, or suspect you have, a medical condition or are taking prescription drugs for depression, migraines, Parkinson’s disease, or psychiatric disorders. Not for use by children. Do not take if you are, or suspect you are, pregnant or if you are lactating.